1. Introduction
Cyclooxygenase (COX) enzymes play a critical role in the biosynthesis of prostaglandins, compounds responsible for mediating inflammation, fever, and pain. Among the two primary isoforms—COX-1 and COX-2—Cyclooxygenase 1 (COX-1) is constitutively expressed in most tissues and is essential for maintaining physiological functions such as gastric mucosal...
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