Diablo 4 doesn’t hold your hand – you’re tossed straight into one of the biggest adventures the series has ever attempted, and it hits you fast. The world’s huge, alive, and packed with stories that don’t just sit neatly in the main plot. You’ll realise quickly that Sanctuary isn’t just a backdrop – it’s layered with side stories, grim events, and fleeting moments of hope that make your journey feel personal. Even if you push through the campaign without getting lost in detours, you’re still talking 50 to 60 hours easily. And that’s before you think about raids, grinding, or chasing down Diablo 4 Items. The game slips in priority missions too – sudden urgencies that cut across whatever you were doing and demand you deal with them right then and there.

Main Campaign Scope

Story-wise, the numbers are kind of wild. There are 101 main quests, each pulling you deeper into the five regions – from the frozen edges of the Fractured Peaks, through the bleak coasts of Scosglen, across the empty Dry Steppes, into the dusty sweeps of Kehjistan, and finally the thick swamps in Hawezar. They’re all distinct, not just in look but in atmosphere. You’ll deal with different kinds of threats, meet locals with their own baggage, and uncover hints that link the regions together. It’s not just run here and fight – there’s an ebb and flow that keeps you moving but also tempts you to stop and take in the corners of the map.

The Side Quest Overflow

If you’ve got a completionist streak, brace yourself. Across those regions, there are 219 side quests, each giving you tiny pieces of the world that the main mission doesn’t touch. Some are quick fetch jobs, others pull you into long chains with unexpected payoffs. Even if you’re not chasing 100% completion, hitting side quests can boost your gear, open new dialogue, or just hand you moments you’ll remember. They make Sanctuary feel lived-in rather than just a set stage for the main tale.

Expansion – Vessel of Hatred

And just when you think you’ve wrapped things up, the Vessel of Hatred expansion drags you back in – in a good way. It’s not a tiny add-on; it’s 16 to 18 hours of fresh ground set in Nahantu, a place dripping with dangers and unknowns. Here, you’ve got 31 main quests driving a new chunk of the storyline, plus 44 side quests that work like threads, weaving more lore into this jungle setting. Nahantu feels different – more claustrophobic, more alive – and tackling it alongside the expanded gear grind is part of the fun.

The Full Picture

Add it all together, and you’re staring at 132 main quests and 263 side quests across the base game and expansion. That’s a lot of ground, a lot of fights, and a ton of story for players who like digging deep. Whether you’re speeding through for the campaign beats or soaking in every optional encounter, there’s enough here to keep you busy for weeks, especially when you start farming Diablo 4 materials along the way.